Digitization of health records in public health facility and its instant availability in the form of electronic record any where any time health service is yet to be implemented in developing nation like India and other countries. Implementation of EHR framework for Indian health system will improve the work-flow of health services to the population. The framework for all levels of healthcare system enable efficient and continuous care to the patient. The first section of this chapter deals with the different levels of healthcare system in India. The role of Information and Communication Technology in healthcare is described in the second section followed by cloud computing for healthcare IT, Health Information Management, and different type of interoperability standards to exchange data between the various levels of healthcare systems.