Seismic Structural Health Monitoring (S2HM) allows the continuous evaluation of engineering structures to estimate their safety and make real-time recommendations for improvement through data analysis and mathematical models. First time in Colombia, a continuous monitoring network with an academic purpose has been deployed in a 14-story ecofriendly steel-frame building in downtown Bogota. Six 3-component accelerometers started recording in June 2019. As an initial attempt to understand the building's response, with only 25 days of continuously recorded data, the anthropogenic behavior from the ambient vibration-based data was analyzed.Then, following the deconvolution-based seismic interferometry approach proposed by Prieto, et al., 2010, for a 225 daylong monitoring campaign, the Impulse Response Function (IRF) was estimated, from 2 different sources of data: 225 days of continuously recorded data and 49 registered earthquakes, both used as an input in the velocity variation measurements, using a stretching technique. A remarkable M6 earthquake occurred on December 24, 2019, in Mesetas, Meta, yielding a significant change in the building's response, noticed in both sets of data.