SYSTEMATIC is the first book to introduce general readers to systems biology, which is revolutionizing medical research and treatments. In traditional bottom-up biology, a biologist might spend years studying how a single protein works. Systems biology focuses on the "big picture"--studying how the surrounding biological network or system affects the protein's function.
This breakthrough became possible only when powerful computer technology enabled researchers to process massive data to study complete systems, and has led to progress in the study of gene regulation and inheritance, cancer drugs personalized to an individual's genetically unique tumor, cancer vaccines, and the discovery that transplanting cells from the gut of a malnourished person into his well-nourished twin's intestinal system causes the healthy person to become malnourished regardless of how well or how much he eats. Similarly, cells transplanted from an obese person can cause the slender host's metabolism to switch toward obesity without changing her diet or activity level. Much of what we have taken for granted is being revised by systems biology.
Research biologist Jim Valcourt gives readers an animated and in-depth guided tour of how systems biology is having a major impact on science and medicine.
A brilliant young scientist introduces us to the fascinating field that is changing our understanding of how the body works and the way we can approach healing.
SYSTEMATIC is the first book to introduce general readers to systems biology, which is improving medical treatments and our understanding of living things. In traditional bottom-up biology, a biologist might spend years studying how a single protein works, but systems biology studies how networks of those proteins work together--how they promote health and how to remedy the situation when the system isn't functioning properly.
Breakthroughs in systems biology became possible only when powerful computer technology enabled researchers to process massive amounts of data to study complete systems, and has led to progress in the study of gene regulation and inheritance, cancer drugs personalized to an individual's genetically unique tumor, insights into how the brain works, and the discovery that the bacteria and other microbes that live in the gut may drive malnutrition and obesity. Systems biology is allowing us to understand more complex phenomena than ever before.
In accessible prose, SYSTEMATIC sheds light not only on how systems within the body work, but also on how research is yielding new kinds of remedies that enhance and harness the body's own defenses.
