All four editors of this title are extremely prominent in the field of PCOS. Although they are all U.S.-based, they are internationally renowned. The book includes the latest diagnostic criteria for PCOS, and comprises the most up to date information about the genetic features and pathogenesis of PCOS.
The diagnostic criteria for PCOS took shape in 1990 following an NIH conference co-organized by Dr. Dunaif, resulting in her classic volume, Polycystic Ovary Syndrome (1992). That title recommended diagnostic criteria of hyperandrogenism and chronic anovlulation with the exclusion of specific disorder of the ovary, adrenal, and pituitary. These criteria dominated the field but were revised in 2003 by a working group of international experts at a conference in Rotterdam. Since then, it has become increasingly clear over the past several years that PCOS is a complex genetic disease resulting from the interaction of susceptibility genes and environmental factors. This volume critically reviews the methodological approaches and the evidence for various PCOS susceptibility genes. Additional familial phenotypes of PCOS and their potential genetic basis are also discussed. In all, this title is comprehensive and replete with the latest in expert recommendations on PCOS. This expert opinion remains critical to guiding practice in PCOS because sufficient data for evidence-based guidelines remains scarce.
From the reviews:
"This monograph is the product of a 2005 meeting of experts in polycystic ovary syndrome (PCOS) that was designed to address disease mechanisms and therapeutic strategies. ? is relevant for a broad audience, but is most relevant for those who are specifically involved in the day-to-day care of women with PCOS as well as those whose research focus is connected to the disorder. ? a useful addition to the library of any physician or investigator with an interest in PCOS." (David A Ehrmann, Doody's Review Service, June, 2008)
